What is the KCE Trials programme?

KCE Trials is a programme of publicly funded, non-commercial, practice-oriented clinical trials. These studies address questions that are generally not studied by industry, despite their high social importance. For example, few studies compare two surgical techniques, or investigate the effect of already existing drugs in groups that are under-represented in commercial studies, such as children or the elderly.

KCE Trials is responsible for the selection, financing and follow-up of the studies, but the studies themselves are carried out in the participating Belgian hospitals. KCE Trials regularly launches calls for study proposals (Calls) and selects the projects that are most likely to improve clinical practice in Belgium (for more information about this selection, see here). KCE Trials mainly focuses on comparative studies. Projects on development and innovation and preclinical studies are not selected.

The clinical studies of KCE Trials:

  • are non-commercial
  • are pragmatic and practice-oriented: Unlike commercial studies, patients receive their treatment in "real life" conditions.
  • are comparative: they compare the effectiveness of existing treatments, which have never been directly compared with each other before
  • can be cost-saving for health insurance, with their results
  • are not limited to medicines or medical devices: they can also have lifestyle adjustments, diets, psychotherapies, diagnostic tests, surgery, etc. as subject
  • collect data that are publicly accessible, and with which detailed and independent cost-effectiveness studies can be carried out.

The working language of KCE Trials is English. This ensures more efficiency in international cooperation. For all communications, publications and activities English is used.

If you wish to be kept informed about the activities of KCE Trials and the Calls, please register here.

Published on: