Useful links on Pragmatic trials Pragmatic trials are trials that are designed to compare treatment options in a real-world setting, as opposed to explanatory trials that test a physiological or clinical hypothesis, typically to develop new drugs or other treatments. Trials can be pragmatic with regards to several features, such as the way sites and patients are recruited, the choice of outcomes, the interventions and their delivery etc.   Pragmatic Trials This NEJM paper gives more information on pragmatic trials:

1. How to receive information on the KCE Trials programme?...

KCE Trials Panel Group of experts who give advice on and prioritisation of clinical topics for their importance to patients and the healthcare system. These same experts may provide additional advice during the call for proposals or development and evaluation of proposals to address these questions or topics. Belgian Coordinating Centre (BCC)

There is an important demand for clinical trials to fill existing evidence gaps and to advance healthcare. In addition to EU funded or co-funded initiatives, the possibilities for obtaining funding for clinical trials in Belgium have expanded over the past years. Trials can broadly be grouped into comparative effectiveness trials of existing interventions and trials to develop a new intervention. Investigators should be familiar with the possible funding programmes and the type of trials funded under each programme. Comparative effectiveness trials

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