Are you looking for funding for a large pragmatic RCT ? Our investigator-led call is currently open for applications, deadline is September 26th. We have extended the deadline compared to previous years to facilitate the setup of collaborations after the summer. Applicants with an idea are always welcome to contact us for a short informal chat about their project (trials@kce.fgov.be). First decisions on the research outlines are expected at the end of this year. In June we organised the BeNeFIT-3 strengthening workshop with the applicants of 9 research outlines (on 27 submitted) that have been shortlisted to develop a full protocol. The final decision in BeNeFIT-3 is expected for March 2024. KCE Trials team |
Funding Opportunities
CALL 2023 Investigator-led is open for applications Our 8th national investigator-led call for proposals is still open ! Funding can be requested to set up a study in Belgium or to recruit Belgium patients in an international study that fits our scope. The study must be randomised, on comparative effectiveness of existing interventions or on drug repurposing. Observational and non-randomised interventional studies are not in scope. The call opened on May 23rd and will close on September 26th 2023 (1PM). All information necessary to apply will be published on the call webpage. |
Progress in funded studies
We are happy to announce the following important milestones have been reached in the trials below:
1st patient randomised
| The purpose of this clinical trial is to investigate the efficacy of continuing hormone therapy after growth of a NeuroEndocrine Tumor (NET) of the stomach, intestine or pancreas that is not hormonally active. The chief investigator is Dr Marc Peeters (UZA, in collaboration with Erasmus MC Rotterdam). This study is jointly funded by KCE and ZonMw (BeNeFIT-2 call). >> more info | |
1st patient randomisedPRIORI 10/07 in NL - 27/07 in BE | A randomized multicenter clinical trial in patients with acute ischemic stroke and carotid artery stenosis undergoing endovascular treatment. The national coordinator in Belgium is Dr Lemmens (UZ Leuven, in collaboration with UMC Groningen). This study is jointly funded by KCE and ZonMw (BeNeFIT-2 call). >> more info | |
Recruitment completed
| Dose reduction of the new generation biologics (interleukin 17 and interleukin 23 inhibitors) in psoriasis: A pragmatic, multicentre, randomized, controlled, non-inferiority study. The study reached target recruitment of 244 patients in The Netherlands and Belgium. The national coordinator in Belgium is Dr Lambert (UZ Gent, in collaboration with Radboudmc).This study is jointly funded by KCE and ZonMw (BeNeFIT-1 call). >> more info | |
CovCOG Recruitment completed | Immediate and long term cognitive improvement after cognitive versus emotion management psychoeducation programs: a randomised trial in covid patients with neuropsychological difficulties The long COVID study completed the recruitment of 130 patients suffering from cognitive problems due to a COVID19 infection. The chief investigator is Dr Sylvie Willems (CHU Liège, in collaboration with UZA CTC). >> more info | |
Recruitment completed | Early administration of Vitamin C in patients with sepsis or septic shock in emergency departments: a multicentre, double blinded, randomized controlled trial. The target recruitment of 300 patients was reached in August 2023. Results are expected for Q2 2024. The chief investigator is Dr Desruelles (UZ Leuven). >> more info | |
Pure-COVID Recruitment closed | PuRe-COVID: Pulmonary rehabilitation for Long COVID study stopped recruitment 30/6/2023 having included 76 of the planned 134 participants. The chief investigator is Dr Lapperre (UZA). The CSR is planned for summer 2024. >> more info | |
IMCOVAS Results will be presented at Belcovac Symposium (15/09) | The IMCOVAS study assessed the immunogenicity and safety of marketed vaccines for COVID-19 after regular schedule and adapted vaccine schedules and routes. The study was led by Dr Katie Steenackers and her team in the centre for vaccination evaluation of U Antwerpen with the participation of ULB Erasme, ITM and UZ Gent. The results will be presented on Friday 15 September on the Belcovac symposium. >> more info |
The KCE Trials complete portfolio comprises 51 studies. more info>>
Impact
The latest scientific publications are presented below, and links to all publications can be found on the last tab of our dynamic dashboards.
More than 26 000 participants have been recruited so far in KCE funded trials!
Check our dynamic dashboard for real-time recruitment data for all KCE Trials funded studies
