Clinical trials in the analysis phase
- ARON: Impact of clinical guidance & point-of-care CRP in children (KCE-181137)
- BENEFICIAL: A Multicentric, Randomised Controlled Clinical Trial To Study The Impact Of Bedside Model-Informed Precision Dosing Of Vancomycin In Critically Ill Children (KCE-181128)
- BLING III: A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients (KCE-17005)
- C-EASIE: Early administration of Vitamin C in patients with sepsis or septic shock in emergency departments: a multicentre, double blinded, randomized controlled trial (KCE-191237)
- GonoScreen: Efficacy of screening STIs in MSM (KCE-181133)
- IMCOVAS: Assessment of the immunogenicity and safety of marketed vaccines for COVID-19 after regular schedule and adapted vaccine schedules and routes: Comirnaty® (Pfizer), Covid-19 vaccine Moderna® (Moderna) and Vaxzevria® (AstraZeneca) (COV201288)
- PRECISE: The impact of high vs standard enteral protein provision on functional recovery following Intensive Care admission: a triple blind randomized controlled trial in mechanically ventilated, critically ill patients (BeNeFIT18574)
Clinical trials which have finished recruiting
- AGNOHSTIC: HYALOBARRIER® GEL ENDO versus no HYALOBARRIER® GEL ENDO following operative hysteroscopy for improving reproductive outcome in women with intrauterine pathology wishing to become pregnant (KCE-17002)
- BeNeBio: Dose reduction of the new generation biologics (IL17 and IL23 inhibitors) in psoriasis: A pragmatic, multi-centre, randomised, controlled, non-inferiority study (BeNeFIT18562)
- BLENDED: Blended Care Psychodynamic Therapy or Cognitive Behavioral Therapy versus Face-to-Face Psychotherapy for Depression: A pragmatic multicentre randomized controlled non-inferiority trial (KCE-17003)
- CareRA 2020: COBRA-Slim with or without fast access to TNF blockade for remission induction in early rheumatoid arthritis (RA) (KCE-16002)
- CovCOG: Immediate and long term cognitive and quality of life improvement after cognitive versus emotion management psychoeducation programs: a randomised trial in covid patients with neuropsychological difficulties (LCOV21-1303)
- PuRe-COVID: Pulmonary rehabilitation for Long COVID (LCOV21-1294)
- RenoMet: Metformin as RenoProtector in Non-Diabetic Patients with Progressive Chronic Kidney Disease (CKD stages 2, 3A and 3B): a multi-centre, practice-oriented, repurposing, double-blind, placebo-controlled, randomized clinical trial (KCE-17006)
- UNLOCK: Nutrition and Locomotoric rehabilitation in Long Covid (LCOV-211306)
Clinical trials open to recruitment
- ALLTogether1: A trial for children and young adults with acute lymphoblastic leukaemia (ALL) (KCE-17010)
- BEST CORNEA: A randomised multicentric parallel group pragmatic trial of Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) versus Descemet Membrane Endothelial Keratoplasty (DMEK) in corneal endothelial decompensation (KCE-201254)
- BONANZA: a randomised controlled trial that is testing whether a management strategy guided by early brain tissue oxygen monitoring in patients in with severe traumatic brain injury improves long term neurological and functional outcomes (KCE-211323)
- CASES: Carotid Artery Stenting during Endovascular treatment of acute ischemic Stroke versus deferred treatment of carotid artery stenosis (BeNeFIT21561)
- COGENIUS: Comparison of conventional and cooled radiofrequency treatment of the genicular nerves versus sham procedure for patients with chronic knee pain: a multicentre, double blind, randomised controlled trial (KCE-201255)
- COL BE PCI: COLchicine in BElgium in patients with coronary artery disease after Percutaneous Coronary Intervention (KCE-211324)
- Foot Drop: A prospective, multi-center, randomized, parallel-group controlled trial to compare conservative versus surgical treatment of foot drop in peroneal nerve entrapment (KCE-191232)
- HYFOIL: Impact on fertility after additional tubal flushing with oil-based contrast versus no additional flushing: a randomised, multicentre, pragmatic trial in infertile women with at least one patent tube at HyFoSy (KCE-191224)
- IODA: Feasibility of conducting a pragmatic, randomized trial that compares Immediate versus Optional Delayed surgical repair for treatment of acute anterior cruciate ligament injury (KCE-181158)
- PEPPER: Determining the optimal strategy for stopping chronic proton pump inhibitor therapy in primary care patients: impact of on-demand use, adjunctive therapies and antacids (KCE-201277)
- PRIMALung: PRophylactic cerebral Irradiation or active MAgnetic resonance imaging surveillance in small-cell Lung cancer patients (KCE-211330)
- PRIORI: Synbiotics in Patients at RIsk fOr preterm birth: a multi-center double-blind Randomized placebo-controlled trial (KCE-201273)
- REPAIR study: Rebuilding Parent young Adult Interpersonal Relationships (BeNeFIT21573)
- SAUNA: Continuing Somatostatin Analogues Upon progression in Neuroendocrine tumour pAtients (BeNeFIT21577)
- SHAPERS: Efficacy and safety of short-course radiotherapy (SCRT) versus total neoadjuvant therapy in older patients with locally advanced rectal cancer: a multicentre, open-label, randomised pragmatic clinical trial (KCE-211331)
- SOPRANO: Prevention of postoperative endoscopic disease recurrence in Crohn's disease (KCE-201262)
- SurLym: Comparison of reconstructive surgery versus no surgery, additional to decongestive lymphatic therapy (usual care), for the treatment of lymphoedema, through a multicentre, pragmatic randomised controlled trial (KCE-191245)
- TreatPaCS: Treatment for preschool age children who stutter: a randomised, multicentre, non-inferiority parallel group pragmatic trial with Mini-KIDS, social cognitive behaviour treatment and the Lidcombe Program (KCE-201257)
Clinical trials starting soon
- BE-Quilt: Comparison of ‘quilting sutures’ with ‘conventional’ sutures and drain placement’ after mastectomy: a multicentre, pragmatic randomised controlled trial (KCE-221361)
- PERSuaDER: PERi-operative Selective Decontamination of the Digestive tract to prevent severe infectious complications after Esophagectomy (BeNeFIT21563)
- RECOVER@HOME: Recovery from disability after geriatric-home rehabilitation versus standard of care: a pilot trial in older patients with disability at hospital discharge (KCE-221383)
Clinical Trials abandoned or stopped before completion
- PELICAN: Localized neuropathic pain: a study to compare topical treatment versus systemic treatment (KCE-17007)
- RESET ASDH: Randomized Evaluation of Surgery in Elderly with Traumatic Acute SubDural Hematoma (BeNeFIT18565)
- KIWI: Bronchodilators for wheeze in young children presenting to primary care: a randomised, placebo-controlled, multicentre, parallel group trial (BeNeFIT18554)
- DUET: Azole-echinocandin combination therapy for invasive aspergillosis. A randomized pragmatic superiority trial (BeNeFIT18558)
- DAWN-antivirals: The DAWN antivirals trial for ambulatory COVID-19 patients (COV201279)
Recruitment in KCE Trials funded studies - dynamic dashboards
Click here to access the dynamic dashboards on recruitment status of studies funded by KCE Trials Programme in Belgian hospitals.
These dashboards are updated every Friday, based on the data entered in SmartSimple by Project Managers of the funded studies.
You can find the guide for Project Managers 'How to update recruitment data in SmartSimple' here.