Study 2026-11 (GCP) Clinical practice guideline on the removal of penicillin allergy labelling

Planned study - Accurate identification of patients with (suspected) penicillin allergy forms the basis of a national strategy and awareness campaign to remove the term ‘penicillin allergy’ from medical records, particularly in hospitals and general practice. Once this reference appears in the file, it is automatically copied into various healthcare environments, leading healthcare providers to avoid penicillin even though there may not be (or no longer be) any medical reason to do so. This can result in the use of less appropriate antibiotics and higher medical costs.

This clinical guideline will focus on the correct identification of patients with penicillin allergy. Approaches used abroad and their results (if they have been assessed) will be taken into account in the development of this clinical guideline. Points to consider for its implementation in routine practice and measures/parameters that could be relevant for monitoring the implementation/adoption of the clinical guideline and its impact might also be addressed.